Cosmetic Grade Preservative Polyquaternium-1/Polidronium Chloride

• CAS No.: 75345-27-6
• Formula: C22h48cl3n3o6
• Molecular Principal Chain: Element Organic Polymer
• Color: Amber to Dark Brown Solid
• Application: Antimicrobial Preservative
• Storage: Room Temperature
• Model NO.: YNR-Polyquat1
• Synonyms: Polidronium Chloride, Pq-1
• CAS: 75345-27-6
• Transport Package: Aluminium Bag Lined with Polyethylene Bag
• Specification: 95% min.
• Trademark: YNR
• Origin: China
• HS Code: 2932999099
• Production Capacity: 100kgs

Product Description

Polyquaternium-1/Polidronium Chloride

Product Description:

Polyquaternium-1 is a very safe preservative, which shows very low acute toxicity in rats.Polyquaternium-1 is slightly toxic orally (LD50> 4.47 ml/l at 40% active in rats). Polyquaternium-1 is not irritating to skin at 40%. The product is not a skin sensitizer and is non-mutagenic.

Polyquaternium-1 is a detergent-type preservative derived from BAK,also named as Polidronium Chloride,PQ-1.Polyquaternium-1 is formulated in the mid of 1980s by Alcon as a preservative for contact lens storage solutions.Nowadays,it is being increasingly used as a presverative in ophthalmic drops for glaucoma, artificial tear solutions and top cosmetic formuations.

Polyquaternium-1 is a cationic polymer prepared by the controlled polymerization of dimethylamine and bis-dichlorobutene, end capped with tris-b-Hydroxyethylamine.

Product Pictures:

Key Technical Parameters:

(1) 95~100% Solid:

Appearance	Amber to dark brown solid
Odor	Without Stimulation
Water solubility	Full Soluble
Free Amine	5.0%
pH	6.0~9.0
Chloride	<30%
Internal standard content	≥95%
Total Number of Aerobic Microbial Count(TAMC)  cfu/g	<10³ cfu/g
Total Yeasts and Molds Count(TYMC) cfu/g	<10² cfu/g

(2) 40% liquid :

Appearance	Light yellow liquid
Odor	Without Stimulation
Molecular Weight	30,000~40,000
Solid Content	≥33%
Chloride	≤10%
Free Amin	≤2.0%
pH	6~9
Water Solubility	100% Soluble
Total Aerobic Microbial Count(TAMC)	<1000cfu/g
Total Yeasts and Molds Count(TYMC)	<100 cfg/g

Applications:

Polyquaternium-1is an antimicrobial preservative, with higher antimicrobial effects and lower ocular irritation.used as bactericide in eye drops,soft lenses product and other ophalmic care products formulation.In skin care formulations,it can help to avoid or reduce the allergy and infection possibility.

*Preservative

*Antimicrobial for use in products targeting mucus membrane or other sensitive tissue

*Antimicrobial for use in dermatological applications and trans-dermal patch pharmaceuticals

*Antimicrobial for use as surface protection for medical devices

Toxicity:

Polyquaternium-1 is a very safe preservative, which shows very low acute toxicity in rats.Polyquaternium-1 is slightly toxic orally (LD50> 4.47 ml/l at 40% active in rats). Polyquaternium-1  is not irritating to skin at 40%. The product is not a skin sensitizer and is non-mutagenic.

Company Overview:

Shipment and Packages:


Company Advantages:

*SGS Audited Supplier
*24 Hours Responce.
*Strong R&D Team and Technical Service.
*One-Stop/Package Service.
*More than 15 years in the chemical raw material field.
*Professional Marketing Team.
*Flexible Payment Terms and Flexible MOQ.
*Strict release procedures .
*On time delivery.

FAQs:

1. Do You Accept Sample Orders?

          Yes,we accept sample orders.
 

      2. What's Your MOQ?
 

           We have no fixed requests on MOQ,it should according to Customers'actual demand.
 

       3. How To Assure The Quality Once Order Confirmed?
 

           We have strict QC/QA management system,and Strict release procedures.
           We prefer to deliver pre-shipment samples by Express Courier before shipment,or you can advise us your quality standard.
 

       4. Can We Have a Preview About The Product Quality before Our Order Despatching?
 

           Sure,we always provide the relative Batach(s)'COA(s) before shipment.

       5.  How Will You Deliver The Goods?

           We have closed cooperation with most famous Shipping companies,Airlines,Express Couriers.
           We'll suggest the best way according to your order quantity.
 

       6.  What Is Your Payment Terms?
 

            We have Flexible Payment Terms.Wire Transfer,Western Union,PayPal and etc.are accepted.
 

       7.   What Is The Leading Time?
 

            The leading time is different based on different quantity,we usually arrange shipment within 3-15 working
            days after order confirmation.

       8.   How to Place Orders?

           You can place your orders on the line www.made-in-china.com directly,or send us your order
           to our official e-mail.